Elevated circulating level of ghrelin in cachexia associated with chronic heart failure: relationships between ghrelin and anabolic/catabolic factors
Ghrelin is a novel growth hormone (GH)-releasing peptide, isolated from the stomach, that may also cause a positive energy balance by stimulating food intake and inducing adiposity. We sought to investigate the pathophysiology of ghrelin in the cachexia associated with chronic heart failure (CHF).
Plasma ghrelin was measured in 74 patients with...
Read moreTreatment of cachexia with ghrelin in patients with COPD
Treatment of cachexia with ghrelin in patients with COPD
Treatment of cachexia with ghrelin in patients with COPD
Ghrelin is a novel growth hormone (GH)-releasing peptide that also induces a positive energy balance by decreasing fat utility and stimulating feeding through GH-independent mechanisms. We investigated whether ghrelin improves cachexia and functional capacity in patients with COPD.
This is an open-label pilot study. Human ghrelin (2 microg/kg...
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